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3Rs-Centre Utrecht Life Sciences
Newsletter, May 2018
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre facilitates the 3Rs in education and animal research in many ways, by providing information and advice about 3Rs models.


 
Plastinated chickens for veterinary education
Claudia Wolschrijn, anatomist within the Pathobiology department at the faculty of Veterinary Medicine at Utrecht University, was awarded a grant from the 3Rs Stimulus Fund of Utrecht University for her research on making air sacs visible in prepared birds. The goal of this project is to reduce the use of laboratory animals in education by making plastinates - animals or sections of animals prepared in a special way to preserve them over time.
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Last chance to register! Symposium 'Improving Science, Advancing Animal Welfare - Towards better In Vitro Practices'
On 1st June 2018, the 3Rs-Centre Utrecht Life Sciences will be holding the symposium 'Improving Science, Advancing Animal Welfare: Towards better In Vitro Practices' in Eindhoven. Leading experts will outline the latest developments on good in vitro method practices and discuss the moral and scientific issues related to the use of fetal calf serum (FCS, or FBS). During this meeting, the new OECD guidance document on good in vitro method practices (GIVIMP) will be discussed. There are only a few spots left, so register on FCS-free.org before May 27th!
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Report: Kick-off HUB Utrecht Advanced In Vitro Methods (U-AIM)
On May 16th 2018, the Utrecht Advanced In Vitro Models (U-AIM) hub was officially launched. The goal of U-AIM is to become a “one-stop shop” where high potential in vitro models are being developed, validated and transitioned to stakeholders. Missed the kick-off? We will catch you up.
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Animated video: Discomfort in laboratory animals
The Animal Welfare Body Utrecht has made a video on discomfort assessment in laboratory animals. The animation provides a brief summary on the topic, and covers such things as the different levels of discomfort, and how the welfare assessment should be done.
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Cellular immunotherapy tested in a 3D bone marrow model
A team of researchers of the UMC Utrecht (departments of Orthopaedics and Haematology) and Catherine Robin, group leader at the Hubrecht Institute (KNAW), collaborated on the development of a 3D in vitro model of the bone marrow niche, for the culture of hematopoietic cells. Using this model, primary multiple myeloma cells could be cultured in vitro, enabling testing of a novel cellular immunotherapy.
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App pulls 3Rs knowledge together
A 2016 study by the European Commission’s Joint Research Centre (JRC) compiled 800 sources of 3Rs knowledge, including organisations, websites and publications. Douglas Connect has recently developed an online application allowing users to easily search and browse this database using criteria such as country, legislative framework and dissemination channel.
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New ALTEX Series: Benchmarks
ALTEX, the open access journal on alternatives to animal experimentation, has a new series. This series, coordinated by Marcel Leist, covers technical issues with in vitro assays. The first installment is 'Normalization of data for viability and relative cell function curves' by Alice Krebs, Johanna Nyffeler, Jörg Rahnenführer, and Marcel Leist. 
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Support our activities!
The 3Rs-Centre ULS maintains the 3Rs databases: The Humane Endpoints Websitethe Interspecies Database and the FCS-free Database. These websites contribute to the refinement, reduction and replacement of animals used for research and are free of charge for their users. The website does not receive any financial support and their future relies on donations and gifts. You can help us with keeping these websites available for free by donating a small amount of money for the maintenance and updating of these databases. We are happy with all donations! The 3Rs Program is part of the charitable fund Friends of VetMed, and as such is exempt from any gift or inheritance taxes. This means that 100% of your donation will contribute towards the purpose specified by you.
Show your support      »



Take a look at international workshops, conferences, meetings and online webinars in the online events calendar of the 3Rs-Centre ULS.
Events       »



Contact details
Yalelaan 2
3584 CM UTRECHT
(+31) 30-2538009
3RsCentreULS@uu.nl
www.uu.nl/3RsCentreULS

Other 3Rs-Centre ULS websites:
www.humane-endpoints.info
www.interspeciesinfo.com
fcs-free.org

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