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Universiteit Utrecht
3Rs-Centre Utrecht Life Sciences
Newsletter, November 2018
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The Centre facilitates the 3Rs in education and animal research in many ways, by providing information and advice about 3Rs models.

Finding 3Rs information: a needle in a haystack?
Scientists are familiar with searching for literature on their subject of interest. Searching specifically for 3Rs methods, however, is something which may require specific search skills. There is a lot of information available, so how to make sure you find everything you are looking for? Saskia Kliphuis is project leader at the 3Rs-Centre Utrecht Life Sciences. Within the Laboratory Animal Science course at Utrecht University, she teaches the subject of formulating a search strategy to find 3Rs information online.
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Report EUSAAT Conference in Linz
From 23 to 26 September 2018, the EUSAAT 21st European Congress on Alternatives to Animal Testing took place. The 3Rs-Centre ULS was present and provides you with the highlights and take home messages of the congress.
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Apply for the International 3Rs Prize
Have you published a paper that describes outstanding and original work that has or could have major impacts on the replacement, reduction or refinement of the use of animals in research? If yes, then you should apply for the annual NC3Rs prize which is sponsored by GSK to recognise a paper published in the last three years with demonstrable 3Rs impacts. This prestigious award consists of a £28k prize grant and a £2k personal award.
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New Online Course in Evidence-based Toxicology
Systematic review and related evidence-based approaches are beginning to be adapted by regulatory agencies like the Environment Protection Agency (EPA), the European Food Safety Authority (EFSA), and the US National Toxicology Program. They provide transparent, objective, and consistent tools to identify, select, appraise, and extract evidence across studies. This new online course will showcase these emerging efforts and address opportunities and challenges to the expanded use of these tools within toxicology. The course is free and available via Coursera.
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Report: Lush Prize Conference 2018
On Friday 16 November 2018, the “Lush Prize Conference 2018” was organized in Berlin, Germany, which preceded the award ceremonies in the evening. The title of the conference and focus of the presentations were on “Is there an end in sight for animal testing?”. Speakers were chosen from the nominees for the different Lush award categories and members of the jury.
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Paper: self-organization of mouse embryonic stem cells into gastruloids
Researchers have demonstrated that small aggregates of mouse embryonic stem cells (ESCs), when stimulated to undergo gastrulation-like events and elongation in vitro, can organize a post-occipital pattern of neural, mesodermal and endodermal derivatives that mimic embryonic spatial and temporal gene expression. These results reveal an unanticipated self-organizing capacity of aggregated ESCs and suggest that gastruloids could be used as a complementary system to study early developmental events in the mammalian embryo.
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Brand new: 3Rs newsletter for animal technicians
Tech3Rs is a newsletter providing animal technicians with the latest news from the NC3Rs. Each issue features updates on recent advances in the 3Rs and highlights new resources, research and events that we think will be of interest to animal technicians. Subscribe for upcoming newsletters and read previously released issues online.
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Call for proposals: Science-Based Refinement Awards
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is now accepting proposals for the 2019 Science-Based Refinement Awards. Applicants may be veterinarians, animal care technicians, researchers, and others who care for the well-being of animals used in science. For 2019, CAAT will offer two awards of $5,000 each. Submission deadline is December 31st, 2018.   
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Support our activities!
The 3Rs-Centre ULS maintains the 3Rs databases: The Humane Endpoints Websitethe Interspecies Database and the FCS-free Database. These websites contribute to the refinement, reduction and replacement of animals used for research and are free of charge for their users. The website does not receive any financial support and their future relies on donations and gifts. You can help us with keeping these websites available for free by donating a small amount of money for the maintenance and updating of these databases. We are happy with all donations! The 3Rs Program is part of the charitable fund Friends of VetMed, and as such is exempt from any gift or inheritance taxes. This means that 100% of your donation will contribute towards the purpose specified by you.
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Take a look at international workshops, conferences, meetings and online webinars in the online events calendar of the 3Rs-Centre ULS.
Events       »

Contact details
Yalelaan 2
(+31) 30-2538009

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