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Universiteit Utrecht
3Rs-Centre Utrecht Life Sciences
Newsletter, November 2017
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre facilitates the 3Rs in education and animal research in many ways, by providing information and advice about 3Rs models.

VitalTissue: Facilitating the use of vital human tissue to replace and reduce animal testing
VitalTissue is an initiative that aims to make hospital-derived viable human tissue available for researchers in the life sciences. The goal of the initiative is improving the translational value of fundamental and applied research to various applications, like drug development or safety testing. Therefore, VitalTissue has the potential to contribute substantially to the replacement and reduction of animal testing. In order to accomplish this, VitalTissue brings together patients, researchers and hospitals.
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2017 Lush Prize winners
The Lush Prize rewards initiatives across science and campaigning that work to end or replace animal testing, particularly in the area of toxicology research. 2017’s Lush Prize winners were announced on 10th November 2017. A prize fund of £330,000 was shared by 18 winners of the Lobbying, Training, Public Awareness, Science, Young Researcher, YR Americas and YR Asia awards. 
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Allen Brain map: Cell Types Database
The Allen Cell Types Database helps to characterize the cellular components of the brain. The database is a multi-modal characterization of cells from the adult mouse visual cortex based on their functional and structural characteristics. Users can investigate the brain's cell types using electrophysiological and morphological data from single cells, and accompanying models of cellular behavior.
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ECNP Preclinical Network Data Prize for published “negative” results
What is believed to be the world’s first prize for published “negative” scientific results, the “ECNP Preclinical Network Data Prize” has been announced by the Preclinical Data Forum of the European College of Neuropsychopharmacology (ECNP). The €10,000 prize, aimed initially at neuroscience research, is to encourage publication of data where the results do not confirm the expected outcome or original hypothesis. It will be awarded by the ECNP’s Preclinical Data Forum, which is a mixed industry and academic group which aims to improve the replicability and reliability of scientific data, especially in drug development.
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OECD Releases New Test Guidelines
The Organisation for Economic Co-operation and Development (OECD) released 17 new, updated, corrected, or deleted guidelines for the testing of chemicals. New or updated test guidelines include methods to address the safety of nanomaterials, tests for acute inhalation and acute dermal toxicity that use fewer animals, a new non-animal method for skin sensitization testing, and updates to incorporate integrated approaches to testing and assessment into test guidelines for eye irritation hazard.
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Review European Commission on Directive 2010/63/EU
A recent Commission review on the animal experimentation Directive stresses the importance of unleashing its potential to seriously replace, reduce and refine the use of animals for testing, research or educational purposes. The main concerns highlighted in the report include a need for improving the efficiency, effectiveness and consistency of project evaluation and authorisation processes before animals are used. The report also highlights the need for more transparency of information about the use of animals. Furthermore, the review identifies the need to ensure high standards of relevant education and training as a means to ensure optimal uptake of the 3Rs. 
Download report     »

Sponsor our activities! 

The 3Rs-Centre ULS maintains the 3Rs databases: The Humane Endpoints Website, the Interspecies Database and the FCS-free Database. These websites contribute to the refinement, reduction and replacement of animals used for research and are free of charge for their users. The website does not receive any financial support and their future relies on donations and gifts. You can help us with keeping these websites available for free by donating a small amount of money for the maintenance and updating of these databases. We are happy with all donations!   
Make a donation       »

Take a look at international workshops, conferences, meetings and online webinars in the online events calendar of the 3Rs-Centre ULS.
Events       »
Contact details
Yalelaan 2
(+31) 30-2538009

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