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3Rs-Centre Utrecht Life Sciences
Newsletter, June 2017
The mission statement of the 3Rs-Centre Utrecht Life Sciences (ULS) is to stimulate the development, acceptance and implementation of methods which can Replace, Reduce and Refine (the 3Rs) animal experiments. The centre facilitates the 3Rs in education and animal research in many ways, by providing information and advice about 3Rs models.


 
Refinement in UU veterinary education: introducing Fluffy cat
The Faculty of Veterinary Medicine at Utrecht University has recently purchased three so-called ‘Fluffy cats’. These furry cat models will be used in the bachelor phase of the veterinary education programme, to facilitate hands-on diagnostic training. That way, skills can be mastered before the actual cat comes into the picture.
Read more       »


 
Preview 3Rs-Centre ULS at World Congress in Seattle
From 20 until 24 August, the World Congress of Alternatives and Animal Use in the Life Sciences will be held in Seattle. The 3Rs-Centre ULS will be present and will contribute to several topics, such as the use of Fetal Calf Serum in cell culture media and the importance of Education & Training in LAS staff. Subsequently, the 3Rs databases will be presented. For a preview, read the abstracts here.
Read more       »


 
RIVM 3Rs Quarterly
The Dutch National Institute for Public Health and the Environment (RIVM) has published a 3Rs Quarterly, reporting on news and developments in the area of 3R methods that can be used for risk assessment of chemical substances and safety and efficacy assessment of pharmaceuticals, including vaccines.
Read more       »


 
NC3Rs and CAMARADES launch new web app for systematic reviews of animal studies
SyRF is a free-to-use online platform for researchers to perform systematic review and meta-analysis of animal studies. It was developed by the CAMARADES group using an NC3Rs infrastructure award. The SyRF app has been designed to help optimise and streamline systematic reviews.
Read more       »


 
Funding opportunity: in-depth critical reviews on research progress in key human disease areas. 
The Humane Society International and Humane Society of the United States are offering grants of up to $10,000 (USD) in funding to support the development and open-access publication of in-depth, independent review articles in discrete areas of human disease/biomedicine by health scientists with relevant expertise. Applications are accepted until 30 June.
Read more       »


 
Two new guidelines for the reduction of animal tests for quality control of veterinary vaccines
JRC scientists supported the development of two guidelines released by the International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH) on the harmonisation of criteria to waive target animal batch safety tests for inactivated and live veterinary vaccines. Their implementation (from May 2018 onwards) is a major step towards international harmonisation and will reduce the number of animals used for batch release testing.
Read more       »


 
EPAA workshop report: Modern science for better quality control of medicinal products
This article summarizes the outcome of an international workshop organized by the European Partnership for Alternative Approaches to Animal Testing (EPAA). As regards the safety testing of biologicals, the workshop participants agreed to actively encourage the deletion of abnormal toxicity tests and target animal batch safety tests from all relevant legal requirements and guidance documents.
Read more       »


 
Guest blog: Human tissue for safety assessment
The UKCRC Tissue Directory and Coordination Centre recently attended a workshop on the use of human tissue for safety assessment jointly hosted by the Safety Pharmacology Society (SPS), the University of Coventry and the NC3Rs. The event was a great opportunity to learn about human tissue in safety pharmacology. But what is safety pharmacology and why is human tissue important? Dr. Helen Prior, SPS secretary and Programme Manager within the NC3Rs explains. 
Read more       »

Take a look at international workshops, conferences, meetings and online webinars in the online events calendar of the 3Rs-Centre ULS.
Events       »
Contact details
Yalelaan 2
3584 CM UTRECHT
(+31) 30-2538009
3RsCentreULS@uu.nl
www.uu.nl/3RsCentreULS

Other 3Rs-Centre ULS websites:
www.humane-endpoints.info
and
www.interspeciesinfo.com

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